Carnitine palmitoyltransferase II (CPT2) deficiency is a rare autosomal recessive disorder of mitochondrial fatty acid oxidation. The most common form of this disorder is characterized by muscle ...

Long-chain fatty acid beta-oxidation disorders (lcFAOD) are a group of inherited metabolic diseases, characterized by the accumulation of disease-specific acyl-CoAs reflecting the enzyme deficiency.

Pyruvate oxidation is critical determinant of pancreatic islet number, beta-cell mass. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2014 / 08 / 140805150851.htm ...

CPT1 is responsible for the formation of acylcarnitine from ACADL (acyl-coenzyme A dehydrogenase, long chain), which is responsible for beta-oxidation of fatty acids within the mitochondria.

Oxidative phosphorylation, 7 peroxisomal beta-oxidation of cerotic acid and pristanic acid, 8 and concentrations of very-long-chain fatty acids 9 were measured as described previously.

Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the ...

Besides increased Bcl-2 in the mitochondria of lung macrophages from bleomycin mice, Carter and colleagues also found two proteins — MCU and Cpt1a — showed a similar increase in expression. The MCU ...