Endogenex said the study "demonstrates substantial and durable reduction in insulin resistance and improvement in beta cell ...

Diabetes is a widespread health condition affecting about 415 million people worldwide. Among these cases, nearly 90% are ...

Defects in insulin sensitivity and β-cell function can occur after gestational diabetes mellitus (GDM). Nonetheless, the relative contribution of these two parameters to the development of ...

Objective: To evaluate the effect of treatment with the dipeptidyl peptidase (DPP)-4 inhibitor vildagliptin on insulin sensitivity and β-cell function in subjects with impaired fasting glucose (IFG).

TIX100 is a small molecule inhibitor of TXNIP, a protein involved in cellular stress response and metabolism. This protein ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial defects, however, ...

Scientists, at the University of Edinburgh, have used living human brain tissue to show how a toxic form of amyloid beta protein damages cell connections in Alzheimer’s. The study reveals even small ...

2007). Table 1 lists some of the GPCRs expressed by beta cells that are known to affect insulin secretion and their natural ligands. As the ligands and function of additional GPCRs are defined ...