Skeletal editing is a modern approach to chemical synthesis. By making precise alterations at the atomic level, researchers ...

This type of resulting molecule is called a benzofuran. Afterward, the imbalanced charges on the benzofuran trigger what’s known as a ‘charge-accelerated sigmatropic rearrangement.’ ...

"We have shown for the first time that the particular molecules, called benzofuran-based molecules, act to inhibit the two enzymes, and in doing so find an alternative way to suppress estrogen ...