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Whether the use of balanced multielectrolyte solution (BMES) in preference to 0.9% sodium chloride solution (saline) in critically ill patients reduces the risk of acute kidney injury or death is ...
Effects of fluid resuscitation with 0.9% saline versus a balanced electrolyte solution on acute kidney injury in a rat model of sepsis. Crit Care Med 2014;42(4):e270-e278. Crossref.
A total of 14.3% of the patients treated with a balanced crystalloid solution experienced a major adverse kidney event compared with 15.4% of patients given saline intravenous fluids (marginal ...
BEST-Fluids received balanced crystalloid and saline solutions at no charge from Baxter Healthcare, which markets Plasma-Lyte 148. The study received no other commercial funding.
Those who received balanced solution were 0.4% (95% confidence interval [CI], -2.1% to 2.9%) more likely to develop AKI than those who received saline. Clinically, patients in the balanced ...
The SALT-ED trial (Saline against Lactated Ringer’s or Plasma-Lyte in the Emergency Department) lasted 16 months and involved 13,347 patients; 6,708 (50.3%) were assigned to balanced ...
On the other hand, the balanced solution is much closer to normal blood levels of sodium and chloride. During a two-year period, Vanderbilt researchers carried out two studies involving 28,000 ...
Balanced fluids, rather than saline, ... 14.3 percent of the patients treated with a balanced crystalloid solution experienced a major adverse kidney event compared with 15.4 percent of patients ...
Collins MG, Fahim MA, Pascoe EM, et al. Balanced crystalloid solution versus saline in deceased donor kidney transplantation (BEST-Fluids): a pragmatic, double-blind, randomised, controlled trial ...
Making lactated Ringer's solution the hospital-wide standard for fluid administration didn't help hard outcomes compared with ...
Compared with standard saline IV fluids, deceased donor kidney transplant recipients who instead received a balanced low-chloride crystalloid solution had a 25% lower relative risk for ...
With colleagues at Vanderbilt, Semler studied 15,000 ICU patients randomly assigned to receive normal saline or balanced fluids like lactated Ringer's, and found that those in the latter group did ...