Some bacterial species simultaneously disrupt the host's DNA damage response through multiple pathways. This can lead to genomic instability and, in consequence, tumorigenic transformation.

These results demonstrate that bacteria allow the cloning, propagation and transfer of large intact and functional genomic DNA fragments and their subsequent direct delivery into cells for ...

Hsu and colleagues discovered bridge RNA when they were studying a transposable element in bacterial DNA called IS110. This genetic chunk can jump around the genome by cutting itself out of one ...

This kit was created to enable the rapid spin column-based extraction of genomic DNA from up to 2 × 10 9 viable bacterial cells (typically from 0.5 to 1.0 mL of culture). It’s suitable for both ...

Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, according to a new study. Researchers analyzed genomic sequencing data available from the ...

Researchers have detailed a bacterial defense mechanism involving two proteins, DdmD and DdmE, that target and degrade plasmids. This system, which uses stable guide DNA, shows promise as a novel ...

as viruses try to inject their DNA into the bacterial genome and bacteria devise cunning methods (e.g. CRISPR) to defend themselves. Many bacterial defense mechanisms remain unexplored but could ...

The genome structure—how genes are organized within DNA sequences in an organism—is fundamental to the processes and functions of organisms. A team at the University of Tokyo has developed a ...

“A typical bacterial genome is three million base pairs long, but time fragments the ancient DNA we recover to an average length of only about 30 to 50 base pairs,” said Christina ...