BRAF V600E mutations are detected in 3%–10% of patients with multiple myeloma (MM) and are associated with more aggressive disease, higher frequency of extramedullary growth and shorter survival.

The most common BRAF mutation is the T1796A point mutation, resulting in a glutamic acid (E) to valine (V) substitution at position 600. BRAF V600E mutations are common in different tumor types ...

Jedd Wolchok, Stephen Hodi, and Antonio Ribas (from Memorial Sloan-Kettering, Dana-Farber Cancer Institute, and UCLA, respectively), will treat advanced melanoma patients who have a BRAF V600E ...

Dr. Karen Kelly explains what a BRAF-V600E fusion is in lung cancer. Dr. Karen Kelly explains the importance of testing for BRAF-V600E fusions is in lung cancer. The videos above were produced in 2020 ...