The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

The live imaging shows how the Bone Morphogenetic Protein (BMP) pathway, which cells use to make and transcribe genes, can ...

Subsequently, KRAS/BRAF activates the Notch pathway or TGFb/BMP pathway through the MEK/ERK ... including MEK inhibitors and mTOR inhibitors, promising effective alternatives to traditional ...