As we begin to define the role of tumour cell metabolism in response to stress, the rational ability to modulate the autophagy pathway in cancer therapy is emerging. Figure 1: Altered capacity for ...

【导读】自噬是一种高度保守的细胞过程，对于维持细胞内稳态以及影响癌症的发展至关重要。3月25日，南昌大学/南方科技大学研究人员合作共同在期刊《Cell Death&Disease》上发表了研究论文，题为“ATP6AP1 promotes cell ...

For example, at the first Keystone Symposium on Autophagy in Health and Disease, held in 2007, Seiji Kondo noted that in the field of cancer research, his colleagues' response when discussing the ...

Liver Health: Autophagy may prevent damage caused to the liver by alcohol, drugs, or conditions known as fatty liver. Cancer: While autophagy may inhibit early tumor growth by removing damaged ...

The study, published in EMBO Molecular Medicine, shows that a process called chaperone-mediated autophagy (CMA) may function as a natural defense mechanism against metastases. Cancer remains one ...

We are interested in dissecting these mRNA splicing events to understand the pathobiology of endometrial cancer beyond the transcriptional effects of steroid hormones. We also are testing our ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...

DELHI: Researchers at the Multidisciplinary Centre for Advanced Research and Studies (MCARS), Jamia Millia Islamia (JMI), have made a significant breakthrough in CAR T-cell therapy, a revolutionary ...