In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...

Noboru Mizushima and Beth Levine discuss how the loss of function analysis of autophagy genes (Atg) in mice has revealed the many roles of the autophagy pathway in mammalian differentiation and ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...