资讯

Although autoantibodies occur in healthy individuals, pathogenic autoantibodies are the key etiologic agent in many autoimmune diseases in humans, most notably lupus erythematosus. In this Review ...
For example, autoantibodies against the cysteine-rich region of ADAMTS13 cause thrombotic thrombocytopenic purpura. 24 In addition, autoantibodies against a cysteine-rich domain of the thyrotropin ...
LaBaer thinks autoantibodies are part of that puzzle. "Knowing autoantibodies that are common in healthy people would help us identify which are really disease related and which ones are not ...
Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein ...
Although common autoantibodies do not appear to cause disease, they appear in as many as 40% of the people tested. It is likely that some of these common autoantibodies have been mistakenly ...
We discovered high-titer neutralizing autoantibodies against interleukin-10 in a child with infantile-onset inflammatory bowel disease (IBD), a phenocopy of inborn errors of interleukin-10 signalin ...
Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, ...
Autoantibodies recognize a broad range of targets. The antibody specialists wondered how it was possible that a COVID-19 infection could produce different antibodies in equal amounts.
Furthermore, a number of autoantibodies in idiopathic inflammatory myopathies, such as dermatomyositis and polymyositis, have been associated with severity of disease and even the presence of ...
Researchers found no association between anti-U1RNP autoantibodies and 3-year ILD progression or mortality in patients with ...
A new study shows that about two percent of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals more susceptible to viral diseases like ...