Several uncontrolled case series have described atypical subtrochanteric or femoral shaft fractures after long-term bisphosphonate therapy; the presumed mechanism is oversuppression of bone ...

Osteonecrosis of the jaw has been reported. Atypical femur fractures have been reported. Evaluate new thigh or groin pain to rule out an incomplete femoral fracture. Bisphosphonates included in ...

While Fosamax was initially hailed as a breakthrough treatment, reports began to emerge soon after its approval linking long-term use of the drug to “atypical femoral fractures”—unusual but ...

Atypical femoral fractures are a potential side effect of the drug. "That's when the endocrinology people worked out that I ...