Autophagy and apoptosis may be triggered by ... The second pathway involves the conjugation of phosphatidylethanolamine (PE) to LC3/Atg8 (LC3 is one of the mammalian homologues of Atg8) by the ...
They set out to identify chemicals that inhibit autophagy in fungi, focusing on one key step in the pathway—the cleavage of the ATG8 protein by the enzyme ATG4. To identify chemicals that ...