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腾讯网
12 天
Nature Methods | 单细胞多模态测序的未来:UDA-seq如何引领新革命?
引言近年来,单细胞RNA测序技术(scRNA-seq)在揭示复杂生物系统和探索遗传学及临床研究中取得了突破性进展。然而,仅依赖单一的转录组信息往往难以区分分子相似但功能差异显著的细胞类别。因此,融合多种模态信息的单细胞测序技术逐渐成为研究热点,通过同时获取单个细胞的多维数据,研究人员能够更全面地解析细胞状态及其 ...
Nature
5 年
Previewing the functional genome with ATAC-Seq and NGS
Unlike RNA sequencing, which provides information about the genes that are being expressed, ATAC-Seq (A(ssay for) T(ransposase)-A(ccessible) C(hromatin using) Seq(uencing)) provides a genome-wide ...
AZoLifeSciences on MSN
14 天
GET Model Unveils Gene Regulation with Unmatched Accuracy Across Cell Types
GET, a novel computational model, accurately predicts gene activity by analyzing chromatin accessibility and DNA sequences ...
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