来自MSN2 个月
A 'chemical metronome': Researchers uncover how astrocytes help the brain's master clock ...They found that astrocytes regularly release a neurotransmitter called GABA, which peaked every 24-hours. This regular pulse was found to act as a kind of chemical metronome, helping to ...
At the centre of this research are astrocytes - star-shaped brain cells that act as the brain's supervisors. These cells manage a crucial molecule called GABA through a specialised transporter (GAT-3) ...
Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acetate uptake in primary cultured astrocytes.
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