We first address the etiopathophysiology of OA and the mechanisms responsible for breakdown of the cartilage extracellular matrix. We then discuss the potential of MSCs for articular cartilage ...

Nanomechanical phenotype of chondroadherin-null articular cartilage. Matrix Biol ... Han. Molecular adhesion between cartilage extracellular matrix macromolecules. Biomacromolecules 2014. 15: 772-780.

“MMP-13 inhibitors might be useful in halting cartilage erosion in ... the collagen network (caused by matrix metalloproteinases [MMPs]) and extracellular matrix proteins.

Hyaline cartilage consists of round chondrocytes, which are cells that produce collagen, embedded within a dense extracellular matrix (ECM). This ECM acts as a physical scaffold ... is to provide an ...

Recent research has uncovered a pivotal role for hyaluronic acid (aka hyaluronan, HA), a glycosaminoglycan found in the ...