"The development of novel treatments demands both a good knowledge of articular cartilage ... and production of extensive extracellular matrix by the grown cartilage cells so that they can be ...

Changes in the extracellular matrix can lead to such chronic diseases ... in one-month-old mutant mice a central area of the articular cartilage at the head of the femur bone in the upper thigh ...

The articular cartilage and meniscus ... how these two tissues and their extracellular matrices (ECMs) initially form. This thesis queries the early molecular events that govern the assembly of the ...

Just a few millimetres thick, articular cartilage plays a crucial role in our musculoskeletal system, since it is responsible for smooth (in the truest sense of the word) movement. However, the ...

Articular cartilage is the cartilage found inside ... the symptoms of osteoarthritis and increase synthesis of the extracellular matrix. Costochondritis describes inflammation of the cartilage ...

These chondrocytes produce large amounts of extracellular matrix composed of collagen ... has a poor regenerative capacity. This cartilage covers the articular surface and has a smooth contour ...

To picture articular cartilage, envision the tough, white coating on the end of a chicken bone. Most of it is a spongy material called extracellular matrix, a mixture of water and fibrous proteins ...

We first address the etiopathophysiology of OA and the mechanisms responsible for breakdown of the cartilage extracellular matrix. We then discuss the potential of MSCs for articular cartilage ...

This blog is a review of OCD of the knee and various treatment options with a focus on matrix-induced ACI (MACI). Osteochondral defects of the knee are lesions in the articular cartilage that ...

More information: S. Nürnberger et al. Repopulation of decellularised articular cartilage by laser-based matrix engraving, EBioMedicine (2021). DOI: 10.1016/j.ebiom.2020.103196 ...