Abstract 程序性坏死（programmed necrosis）作为一种绕过凋亡（apoptosis）耐药机制的受控细胞死亡方式 ... 本综述重点探讨了天然产物通过铁死亡（ferroptosis）、坏死性凋亡（necroptosis）等机制选择性杀伤癌细胞的能力，并解析了其分子作用靶点，如混合谱系激酶结构 ...

Apoptosis is triggered many different ways ... Sometimes engulfed cells survive, even proliferating within their cellular captor or escaping altogether. Necroptosis is a programmed version of necrosis ...

Cells use a variety of programmed cell death mechanisms to maintain homeostasis through cellular self-destruction, including apoptosis, necroptosis, and pyroptosis. Elina is a PhD candidate at the ...

Tumor necrosis factor-α (TNF ... interacting protein kinase 3)-mediated necroptosis has been proposed as an alternative strategy for treating apoptosis-resistant leukemia. However, we found ...

Published in the Chinese Medical Journal, necroptosis shares characteristics with apoptosis (natural cell breakdown) and necrosis (injury-related cell damage), and receptor-interacting protein ...

Researchers identified a Mtb effector protein, mammalian cell entry 3C (Mce3C), which promotes host cell necroptosis while inhibiting apoptosis. Mechanistically, Mtb Mce3C can bind host cathepsin ...