APOE ferries cholesterol throughout the body and brain and is thought to play a role in depositing or sweeping away sticky beta amyloid plaques, which are one hallmark of Alzheimer’s.” ...

First, some of the exchange of cholesterol esters between HDL and peripheral cells is known to be bidirectional, in part mediated by the scavenger receptor class B1. [13] This observation gives ...

Over the years, those lipid deposits haven't received as much ... Different forms of the protein, called for apolipoprotein E (APOE), have varying efficiencies in their ability to move fat in ...

This vulnerability could be modified by adjusting the intake of folates. Similarly, the APOE gene affects cholesterol metabolism, whereby carriers of the APOE4 variant are at a higher risk for ...