来自MSN2 个月
Brain immune cells amplify damage caused by Alzheimer's risk gene, study finds
There are three major forms of APOE protein in humans. Compared with the most common version of the protein—APOE3—the APOE4 protein increases risk and APOE2 decreases risk for Alzheimer's disease.
来自MSN10 个月
Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene ...
In addition to demonstrating the direct binding and stabilizing effects of the P3S-humanin on the harmful APOE4 protein, the investigators showed that giving the P3S microprotein to mice ...
Nature8 年
Metabolic shifts toward fatty-acid usage and increased thermogenesis are associated with ...
The Apolipoprotein E (APOE) gene encodes for three isoforms in ... and fecal TG determined as above. Protein expression levels were analyzed by western blot using antibodies against UCP1 (Santa ...