The aim of our study was to investigate antiproliferative effects of PEP005 in a panel of colon cancer cell lines that expressed various levels of PKCδ and to evaluate the effects of PEP005-based ...

Targeting CDC-like kinases 2 and 3 (CLK2 and CLK3) has emerged as an effective therapeutic strategy in cancer treatment, with several compounds currently in clinical development.

siRNA mediated silencing of Wilms tumor gene-1 (WT1) in leukemia cell lines No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2005 ASCO Annual Meeting. This ...

Design and development of high-drug-load paclitaxel (PTX)-antibody conjugates: Synthesis and preliminary evaluation of soluble paclitaxel (sPTX) and sPTX-cetuximab conjugates This is an ASCO Meeting ...