Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies.
and epitope-optimized antibody–drug conjugates, to bispecific antibodies and chimeric antigen receptors for cell-based therapies. RubrYc’s collaboration model includes options for co-discovery ...
Explore how machine learning is transforming immunology—from epitope prediction to smarter vaccine design—plus key challenges ...
Recombinant Monoclonal Antibodies: It is made up of identical antibody chains that target the same epitope of a certain antigen. Recombinant Multiclonal Antibodies: They are a mix of carefully ...
The antibody 7E11 binds to the intracellular epitope of PSMA and can reach ... Ruggiero A, Holland JP, Hudolin T, Shenker L, Koulova, A, Bander N, Lewis JS, Grimm J (2011) Targeting the internal ...
The initial antigens ... homeostatic antibodies may facilitate the onset of CD in susceptible individuals later in life. Zhao: We did identify a dominant B-cell peptide epitope in CD patients ...