A bold funding initiative aims to help scientists predict a T cell’s target antigens, with implications far beyond cancer ...

in the innate mechanisms of antigen binding by professional APCs. DCs and macrophages express a variety of lectins and scavenger receptors that facilitate direct or indirect recognition of ...

A study from Adamson University (AdU) is seeking to ontribution to cancer immunotherapy in the development of vaccines ...

T-cell mediated immune responses specific for peptides from the murine scFv antigen-binding domain of ... at residue 224 was necessary for FMC63 recognition, but insufficient to restore ...

Study reveals B cells suppress mutations during rapid division, enhancing immune response and offering critical insights for ...

Recipient T cells recognize donor antigens via two distinct pathways ... the semidirect pathway involving T-cell recognition of donor MHCs transferred on recipient APCs. The contribution of ...

Some recent studies have suggested that T cells can become activated via recognition of donor MHC molecules transferred on recipient antigen-presenting cells (semidirect pathway). Activation of T ...