To remove N-linked glycosylations, protein lysates were incubated with ... human T-cells result in tonic signaling in the absence of antigen and lead to an exhausted T-cell phenotype ...

Gennova Biopharmaceuticals Ltd. on Tuesday announced that it is partnering with the Coalition for Epidemic Preparedness Innovations (CEPI), a subsidiary of Emcure Pharmaceuticals Ltd. for the ...

They need to hunt for clues. One way they can do that is with a carcinoembryonic antigen test. It measures a protein called CEA in the blood. People with some types of cancers have higher than ...

Many HIV tests look for p24 antigen in addition to antibodies to HIV. These are sometimes called fourth-generation tests. One distinctive HIV antigen is a viral protein called p24, a structural ...

The method triggers immune responses that inhibit melanoma, triple-negative breast cancer, lung carcinoma, and ovarian cancer ...

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved trofolastat (RoTecPSMA), the first prostate-specific membrane antigen (PSMA)-targeting product authorised for use with ...

This article explores how automation is transforming proteomics by streamlining proteoform analysis, boosting throughput and ...

CEPI is providing US$4.5 million to non-profit Fondazione Biotecnopolo di Siena (FBS) for proof-of-concept research that will explore whether producing antigens in C1 filamentous fungus—applying ...

Cryptic antigens are part of a protein—known as epitopes—that are usually hidden or inaccessible to the immune system and may be present in tumor cells. By targeting these antigens ...