The investigators showed that in vivo gene therapy in mice mediated the destruction of human eosinophils and antibody-dependent cellular cytotoxicity activity against human eosinophils.
Compared to antibody production, the efficiency of rAAV production is expected to increase at least 1,000 times. Michael Baker says once the bottleneck is cleared, gene therapy treatments will rea ...
It's early days for xenotransplantation, but eGenesis, Eledon, United Therapeutics and more are working to develop solutions to make this approach a viable option and help ease the organ shortage ...
Adeno-associated virus (AAV)–mediated gene therapy was one of the focal points of this year's Muscular Dystrophy Association conference. Here, Barry Byrne, MD, PhD, University of Florida ...
Yale scientists have discovered a promising way to trigger immune responses against certain tumors, using a lupus-related ...
"Equally exciting is the discovery that this lupus antibody delivers genes to cells without needing any help from a virus, meaning it could be used to transform gene therapy strategies." ...
Yale scientists have discovered a promising way to trigger immune responses against certain tumors, using a lupus-related antibody that can slip, undetected, into "cold" tumors and flip on an immune ...
The company shared an update on Elevidys (delandistrogene moxeparvovec-rokl), the only approved gene therapy in patients ... effect of Elevidys and other AAV-mediated gene therapies and is ...