Previously we demonstrated an approach to introduce genetic diversity in antibody libraries, where diverse natural CDRs are combined into an antibody framework 11, using only CDR-encoding gene ...
Figure 1: Recombination of V,D, and J Germline Genes into a Functional Antibody (Market and F. Nina Papavasiliou, PLos Biology 1:24-27 Figure 2. Map of the 1Mb human Immunoglobulin heavy chain locus ...
Scientists from Banaras Hindu University (BHU) are conducting a groundbreaking study at the ongoing Maha Kumbh in Prayagraj to analyse the genetic diversity of attendees and assess immunity levels ...
Existing monoclonal antibody development technologies, such as hybridoma technology, suffer from a loss of diversity due to cell fusion efficiency, and phage display technology creates antibodies ...