Despite recognizing an epitope on HIV-1 gp41 that partially overlaps with those from broadly neutralizing antibodies, mAb 13H11 is non-neutralizing. Now the crystal structure and binding studies ...

Researchers have now visualized the molecular structure of the LAG3 protein. They describe the crystal structure of LAG3 and how it interacts with molecules produced by cancer cells.

Crystal structure: An antibody (red and green) binds to the HCV surface protein "E2" (purple). (IMAGE) German Center for Infection Research ...

In the September 25 PNAS online, researchers led by Chris Dealwis at the University of Tennessee in Knoxville published the first crystal structure of a monoclonal antibody to the amyloid-β (Aβ) ...

Crystal structure and biolayer interferometry of germline VRC01 binding 426c core immunogen. Image provided by Connor Weidle. In this study, the authors characterize how immunogens that better mimic ...

The two types of antibody crystal structures solved by the team revealed exactly how different amino acids are arranged around the phosphohistidine to bind it tightly.

Core structure of camelid antibodies. ... In addition, there is an excellent shape complementarity between the two protein domains in the crystal structure of VHH-antigen complex.

Many questions remain. How the CDR loop that houses most of the different contacts might relate to oligomer properties is unknown, as is whether the oligomer-binding antibody 12A11 can prevent ...

Treatment for heparin-induced blood disorder revealed in structure of antibody complex. ScienceDaily . Retrieved April 21, 2025 from www.sciencedaily.com / releases / 2015 / 10 / 151006132033.htm ...

This paper presents the X-ray crystal structure of the complete extracellular portion of SIRP? co-crystallized with the Fab fragment of the OX117 monoclonal antibody. ... Crystal Structure of Signal ...