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Some decongestants might interfere with blood pressure medication. UVA Health suggests avoiding nasal sprays that have oxymetazoline, such as Afrin. Non-steroidal anti-inflammatory drugs (NSAIDs ...

Decongestants are a type of medication that helps clear a stuffy nose or nasal congestion. You may need a decongestant to reduce stuffiness and breathe easier if you have a cold or allergies.