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CRISPR改写免疫疗法!Cancer Cell|科学家激活NK细胞抗癌潜能,直击肿瘤 ...
世界卫生组织数据显示,全球每年约 1930 万癌症新发病例中,1000 万人因癌离世。尽管免疫检查点抑制剂(如 PD-1 抗体)已革新癌症治疗,但仍有大量患者面临「无响应」或「耐药」难题。其中,自然杀伤细胞(NK 细胞)作为抗癌第一道防线,其活性常被肿瘤微环境抑制 —— 而 IL-15 作为调控 NK ...
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