A better understanding of the molecular mechanisms leading to aneuploidy holds promise for the development of cancer drugs that target this process. Another example of cancers without aneuploidy ...

A new tool generates and labels customized aneuploid cells in living tissue to observe the behavior of these cells in ...

it may be possible to take advantage of a cancer cell's genomic characteristics in order to destroy it. One of the characteristics that's often found in cancerous cells and not in healthy cells is ...

A new study led by researchers from Tel Aviv University shows, for the first time, how an abnormal number of chromosomes (aneuploidy) -- a unique characteristic of cancer cells that researchers ...

"For a long time, we could observe aneuploidy but not manipulate it. We just didn't have the right tools," said Sheltzer, who is also a researcher at Yale Cancer Center. "But in this study ...

Researchers used CRISPR technology to remove entire chromosomes in melanoma, gastric cancer, and ovarian cell lines Eliminating aneuploidy compromised cancer cells' ability to form tumors ...

Healthy human cells have 23 pairs of chromosomes, but it’s been observed for over a century that the majority of cancer cells have extras. This condition is known as aneuploidy, but its exact ...

the five-year rate of death from cancer was 72 percent. Aneuploidy-related first carcinomas were diagnosed at a more advanced stage than were carcinomas originating from diploid or tetraploid ...

The findings, said the researchers, suggest that selectively targeting extra chromosomes may offer a new route for treating cancer. The study was published July 6 in the journal Science. Human cells ...

Alterations in chromosome number can play a role in cancer progression. An analysis of recurrent aneuploidies, such as the duplication of the long arm of chromosome 1, revealed that it was required ...

whether they cause cancer or are caused by it. "For a long time, we could observe aneuploidy but not manipulate it. We just didn't have the right tools," said Sheltzer, who is also a researcher at ...