In the latest PNAS paper 2, aneuploidy as the functional genetic basis of cancer passes both these tests in ways that should be of interest to biotechnologists of a variety of stripes. Of all the ...

Aneuploidy—when the cells of an organism contain more or fewer than the standard number of chromosomes for its species—is found in greater than 90 percent of all human cancers. But how exactly it ...

The researchers found that a significant number of cancer cells are aneuploid, and that they are more vulnerable than healthy cells. They also discovered that aneuploidy increases the sensitivity ...

More information: Jan-Eric Bökenkamp et al, Proteogenomic analysis reveals adaptive strategies for alleviating the consequences of aneuploidy in cancer, The EMBO Journal (2025). DOI: 10.1038 ...

Mosaic variegated aneuploidy syndrome (MVAS) is an autosomal recessive disorder characterized by mosaic aneuploidy. Its clinical manifestations include growth and developmental delay, congenital ...

Chromosomal abnormalities occur in 0.1% to 0.2% of live births, and the most common clinically significant aneuploidy among live-born infants is Down syndrome (trisomy 21). Other sonographically ...