The 3.0 Å crystal structure of T. thermophilus Ago complexed with a 5′-phosphorylated (5′-phos-T 1 GAGG 5 TAGTA 10 GGTTG 15 TATAG 20 T) 21-base DNA guide strand is shown in Fig. 1a, with ...

Here we present the structure of this complex, revealing a remarkable rearrangement of the DNA following base-excision to a structure similar to that observed in cisplatin cross-strand adducts ...

Scientists determine structure of a DNA damage 'first responder' Date: March 21, 2022 Source: Memorial Sloan Kettering Cancer Center Summary: The results of this collaborative project overturn ...

4-Strand DNA Structure Found in Cells. A newly discovered unusual nucleic-acid structure might have a role in regulating some genes. By Alison Abbott & Nature magazine.

Recent efforts in our lab have focused on complexes mediating DNA double strand break (DSB) repair. These range from the Structure Maintenance of Chromosome Smc5/6 complex involved in rescue of ...

Structure of deoxyribozyme 9DB1, where we can see the synthetic strand of DNA (in green) once it has catalysed the ligation of two RNA strands (in orange), joined at the point which is represented ...

Though scientists have learned much about DNA damage and repair over the past 50 years, important outstanding questions remain. One particularly bedeviling puzzle is how a repair protein called the ...

(A strand of DNA can be sequenced in either direction, but code is meant to be read in only one. The researchers suggest in their paper that future, improved versions of the attack might be ...

The discovery builds upon the landmark 1953 breakthrough when Watson and Crick revealed DNA’s double-helix structure. For replication to occur, the helix must first unwind, splitting into two ...

DNA, or deoxyribonucleic acid, is fundamental to your growth, reproduction, and health. Read about its basic function and structures.

The structure of DNA made visible Date: August 31, 2015 ... -- the very first direct image of a DNA strand with resolution 20 times better than that achieved by Di Fabrizio in 2012.