Vect-Horus has a clinical-phase solution to a key drug development challenge: crossing the blood–brain barrier (BBB). By targeting receptors on the barrier, Vect-Horus is empowering partners ...

ABL Bio’s first-in-class bispecific antibodies for Parkinson’s disease combine unprecedented blood–brain barrier penetration with a robust mechanism of action for improved therapeutic efficacy.

were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to ...

Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in ...

In addition to a thick skull, the blood-brain barrier (BBB), a natural protective membrane, prevents microscopic intruders such as toxins and pathogens from entering the nervous system.

Researchers led by CHLA’s Jonathan D. Santoro, MD, have identified signs of neuroinflammation and dysfunction of the blood-brain barrier among patients with Down syndrome Regression Disorder (DSRD).