A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...

The study reveals lariocidin, a potent ribosome-targeting antibiotic, with unique mechanisms that could combat drug-resistant ...

Given the essential role of rRNA in protein synthesis, it is not surprising that many antibiotics target the ribosome and its rRNA components. Antibiotics such as aminoglycosides, tetracyclines, and ...

or aminoglycosides partially reduced α-toxin expression. [61,66] Linezolid (an oxazolidinone), a synthetic protein inhibitor that binds to the 50S ribosome to prevent the formation of the 70S ...

Gentamicin, an aminoglycoside, binds to the prokaryotic ribosome, inhibiting protein synthesis in susceptible bacteria. It is bactericidal in vitro against Gram-positive and Gram-negative bacteria.