Liddle syndrome is an autosomal dominant disorder caused by hyperactivity ... metabolic alkalosis in the setting of low plasma renin and aldosterone, low rates of urinary aldosterone excretion ...

The investigational aldosterone synthase inhibitor lorundrostat effectively lowered 24-hour BP for adults with well-treated, uncontrolled and “true” treatment-resistant hypertension, according to data ...

Sodium reabsorption is mainly controlled by aldosterone, a steroid hormone synthesized in the zona glomerulosa of the adrenal gland, secondary to renin stimulation via angiotensin II and to ...

The finding that angiotensin II and aldosterone are proinflammatory ... the importance of RAAS inhibition has emerged in several clinical disorders. The careful monitoring of plasma potassium ...

Adrenal glands can also be impaired if there is a disorder in the pituitary gland, as it signals the adrenals to make certain ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Addison’s disease, also called primary adrenal insufficiency, is a rare disorder that occurs when the body doesn’t make enough of two hormones called cortisol and aldosterone. Cortisol is an ...