随着年龄增长， 人体免疫系统逐渐出现功能紊乱，表现为对感染、肿瘤及疫苗的反应减弱，同时伴随慢性低度炎症状态的增强。这种现象被称为“炎症老化”，是多种老年疾病（如心血管病、神经退行性疾病和自身免疫病）的重要诱因。

But telomerase isn’t sufficient to prevent T cell senescence, sending scientists searching for another key mechanism responsible for guarding against T cell aging. The researchers, a team at ...

Pro-aging effects of T cells: T cells exert a long-range pro-aging influence on nearby brain cells, particularly oligodendrocytes and pericytes, through mechanisms linked to immune signaling and ...

近日，一篇发表在国际杂志Aging Research上题为“Human T cell development and aging: Remodeling throughout the lifespan”的研究报告中，来自中国暨南大学等机构的 ...

More information: Lipeng Mao et al, Human T cell development and aging: Remodeling throughout the lifespan, Aging Research (2024). DOI: 10.26599/AGR.2024.9340021 ...

Share on Pinterest Researchers have discovered that T cells in the body can be reprogrammed to slow down and even reverse aging. Yagi-Studio/Getty Images Scientists are constantly looking for ways ...

Aging significantly impacts the immune system, notably through the involution of the thymus, which reduces T cell production.

The objective was to identify some of the mechanisms involved in the failure to enhance myelin repair associated with regulatory T cell aging to modulate them in a more specific manner", clarifies ...

A research team from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences has revealed that aging specifically impairs the generation of CD8 + tissue resident ...

Vitamin D supplements may help prevent the loss of telomeres, DNA sequences that shrink with aging, a large study shows. But ...

Detailed mapping of 1.2 million brain cells has revealed that not all cell types age in the same way and that some – found in a specific ‘hot spot’ – are more sensitive to the aging process.