为探究 β 2 - 受体阻滞剂(BBs)对胃癌(GC)患者预后及化疗反应的影响,研究人员开展回顾性队列研究,发现 BBs 对不同 GC 亚型影响不同,为癌症治疗提供新依据。
The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets. In contrast, β2AR and essentially all of the other GPCRs are present at very low ...
For example, for conditions such as asthma or catecholamine-resistant shock, β-adrenergic receptor agonists that have the capacity to signal through G proteins without desensitization mediated by ...
Pancreatic cancer, one of the deadliest types of the disease, has been linked to obesity and higher stress levels, a new UCLA ...
Stress hormones activate the β-adrenergic receptor/PKA pathway, while obesity-related signals mainly use the PKD pathway. This suggests that both stress and obesity can fuel pancreatic cancer growth ...
Specifically, preliminary data suggest that these mescaline derivative compounds may interact with a variety of important neurological receptors, including the α2A adrenergic receptor (ADRA2A), the ...
So that’s where we started looking.” Mice exhibit a well-documented circadian rhythm and ECG parameters comparable to humans, so the researchers pharmacologically blocked the SNS using the ...
Stress hormones activate the β-adrenergic receptor/PKA pathway, while obesity-related signals mainly use the PKD pathway. This suggests that both stress and obesity can fuel pancreatic cancer ...
Propranolol HCl 60mg, 80mg, 120mg, 160mg; sust-rel caps. Propranolol, a nonselective β-adrenergic receptor blocker, does not possess autonomic nervous system activity. Propranolol generally ...
Specifically, preliminary data suggest that these mescaline derivative compounds may interact with a variety of important neurological receptors, including the α2A adrenergic receptor (ADRA2A ...
Timolol (as maleate) 0.25%, 0.5%; oph soln; contains benzalkonium chloride. Timolol maleate is a beta 1 and beta 2 (non-selective) adrenergic receptor blocking agent that does not have significant ...