How do cells forming organs or repairing tissues know when to stop growing? Adhesion receptors act as molecular fingertips that sense the environment and then coordinate behaviors. Aa Aa Aa In ...

In this international study, the scientists showed that one of the adhesion G protein-coupled receptors – GPR133 – is activated by the androgenic steroid hormone 5α-DHT. Created in BioRender.

Structure and the tethered activation mechanism of aGPCRs. (A) The basic structure of aGPCRs. This article highlights the critical role of mechanosensitive aGPCRs in human health and disease ...

Adhesion G protein-coupled receptors (aGPCRs) are the second largest family of these receptors in humans. As their name suggests, they help cells adhere, or stick to each other, and send signals ...

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G ...

View Full Profile. Learn about our Editorial Policies. “Focus has been on how cells become mechanosensitive, how cell adhesion became mechanosensitive through the recruitment of mechanosensitive ...

The majority of cell signaling, cell-cell adhesion or parasit-host interactions is due to interactions between carbohydrates from the extracellular system and and receptors from the respective cell ...

Diseases associated with mechanosensitive adhesion G protein-coupled receptors (aGPCRs). Different colors are used to distinguish diseases related to different receptors. SHANNON, CLARE ...