As their name implies, these receptors have two functions: they contribute to cell adhesion by participating in cell–cell or cell–matrix interactions; and they respond to the stimulus of cell ...

Over the past twenty years, intensive research has enabled us to identify components of specific signalling pathways downstream of an array of adhesion and growth-factor receptors. The first ...

This important study presents a compelling theoretical framework for understanding phase separation of membrane-bound proteins, with a focus on the organization of tight junction components. By ...

Adhesion GPCRs (aGPCRs), which comprise 33 receptors, participate in a variety of physiological processes such as immune responses, organ development and cellular communication. These receptors ...

At cell-cell junctions, adhesion receptors at the cell surface are linked via adaptor proteins to the cytoskeleton, a structural scaffold inside the cell composed of filamentous proteins like actin.

However, whether and how presynaptic adhesion molecules trans-synaptically regulate the localization and stabilization of postsynaptic neurotransmitter receptors remained largely unclear.

Adhesion G protein-coupled receptors (aGPCRs) are the second largest family of these receptors in humans. As their name suggests, they help cells adhere (stick to each other), and send signals ...

To study this process, the researchers used human breast cancer cells depleted of junctional adhesion molecule-A (JAM-A), a cell adhesion receptor that is localized at cell-cell junctions in polarized ...

The force direction between ligand and receptor is tangential to the cell or parallel to the substrate, leading to different cell adhesion behavior. Preliminary studies showed that integrins ...

Only a relatively small set of flagellar adhesion receptors have been discovered so far, often being highly specific to the species and strain of bacteria, and the host. Similarly, flagella are ...

It is known that integrin receptors send important signals into the cells and when these are missing cancer cells no longer effectively form tumors. However, it turns out that this can also ...