In response, the industry has begun a new round of layout in the obesity treatment sector, with several pharmaceutical companies focusing on other new therapeutic targets, such as the Activin ...

iBio, Inc. Activin E antibody demonstrates significant decrease in fat in obese mice by reducing visceral fat depots, which are strongly linked to increased risk of cardiovascular and metabolic ...

This study showed that a subset of cells called osteoclastogenic fibroblasts expresses a protein, activin A, which causes the breakdown of the bones. Because of this discovery, novel medical ...

The pituitary is the target for and site of synthesis of several growth factors that modulate hormone production and regulate pituitary cell growth. [2] Some growth factors are critical for normal ...

Activin A, also secreted by the placenta ... but the use of bromocriptine to suppress the release of prolactin from the pituitary is currently under investigation and may be considered in patients ...

In-Licensing of novel activin E antibody underscores iBio’s commitment to delivering meaningful benefits to patients living with obesity and cardiometabolic diseasesSAN DIEGO, April 22, 2025 ...

SAN DIEGO, Jan. 07, 2025 (GLOBE NEWSWIRE) -- iBio, Inc. (NYSEA: IBIO), an AI-driven innovator of precision antibody immunotherapies, in collaboration with AstralBio Inc., announced today the ...

iBio (IBIO) in collaboration with AstralBio announced the development of an antibody that inhibits the function of Activin E, a promising therapeutic target for cardiometabolic disorders and ...

One of the categories of drugs currently under investigation for the treatment of muscle loss includes drugs that inhibit the activation of the activin receptor or the signaling pathway activated ...

Strong synergistic effect on fat mass (77% reduction) was observed when the Activin E antibody was combined with a GLP-1 receptor agonist, resulting in total weight loss of 35.3%, 7.5% greater ...

This study demonstrated how these fibroblasts expressed an abundant amount of activin A, a molecule that regulates different physiologic functions of the body. The presence of activin A is said to ...

Developing an antibody against Activin E, a challenging and elusive target, highlights the robust capabilities of the technology to deliver innovative therapeutics, and contributes to iBio's pipeline ...