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相比之下,TNFR2 介导的 EAE 诱导的 CNP 减轻与性别和性别染色体无关。然而,在两种不同的神经病理性疼痛模型(EAE 和慢性压迫性损伤)中,TNFR2 激活后 CNP 的减轻依赖于性腺激素 Activin-A。这表明性腺来源的因子通过一种共同机制影响 TNFR2 介导的疼痛缓解 ...
Inhibin/activin subunits are expressed in a variety of tissues, including ovary, testis, placenta, adrenal, kidney, brain and pituitary gland. Inhibin A and Activin A have been reported to ...
This study showed that a subset of cells called osteoclastogenic fibroblasts expresses a protein, activin A, which causes the breakdown of the bones. Because of this discovery, novel medical ...
The pituitary is the target for and site of synthesis of several growth factors that modulate hormone production and regulate pituitary cell growth. [2] Some growth factors are critical for normal ...
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