A conformational change of myosin head upon binding to actin filament must be responsible for this actin-activated ATPase, but structural information on the actomyosin rigour complex is still ...

Myosin heads have a step size: that is, they move a certain distance each time they hydrolyze an ATP molecule. Therefore, multiple actin molecules have to be bound to the polymerase complex ...

研究人员为探究 Myosin 5a 在糖尿病膀胱病（DCP）中的作用，开展相关研究，发现其或可成治疗靶点。 糖尿病膀胱病研究新突破：Myosin 5a 成为潜在治疗靶点 在全球范围内，糖尿病（Diabetes mellitus，DM）如同一场悄无声息的健康危机，不断蔓延。据统计，我国糖尿病 ...

Using electron-cryo microscopy to take 3D snapshots of myosin V and actin interacting ... treatment of the myosin that might alter the complex's natural mechanism of action.

Stefan Raunser and Elmar Behrmann from the Max Planck Institute of Molecular Physiology in Dortmund have now managed to image the actin-myosin-tropomyosin complex with an unprecedented accuracy of ...

Stefan Raunser and Elmar Behrmann from the Max Planck Institute of Molecular Physiology in Dortmund have now managed to image the actin-myosin-tropomyosin complex with an unprecedented accuracy of ...

The actin and myosin complex (actomyosin) generates contraction force of a muscle utilizing the adenosine triphosphate (ATP) hydrolysis reaction. Many attempts have thus been made to explain the ...

A cartoon showing the asymmetry in the weak binding between myosin and actin that biases the direction of their dissociation. Credit: Osaka University Researchers love to use cartoons to demonstrate ...

Clinical evaluations demonstrated that the Carney complex cosegregated with ... localizes to the actin-binding domain of the perinatal myosin head, and is close to the ATP-binding site.

Actomyosin is a protein complex composed of actin and myosin. It is found in muscle fibers where it plays a role in muscle contraction. Actin is one of the most abundant proteins in eukaryotes.

I. Rayment, H.M. Holden, M. Whittaker, C.B. Yohn, M. Lorenz. K.C. Holmes, R.A. Milligan, "Structure of the actin-myosin complex and its implications for muscle ...