Notably most of the evidence, in particular from animal studies, of the complement system participating in the development of AAV comes from MPO-ANCA-positive vasculitis. This observation is ...

Evidence of an important genetic contribution to ANCA-associated vasculitis has been growing, including evidence of a familial association. 6 The most convincing association has been with the ...

New-onset ANCA-positive small-vessel vasculitis is a rare but possible complication of COVID-19 vaccination. New-onset ANCA-positive small-vessel vasculitis is a rare but possible complication of ...

ANCA vasculitis is characterized by a loss of ... Enrolled patients tested positive for antibodies to PR3 or MPO, had an estimated GFR of greater than or equal to 15 mL/min/1.73 m 2, and had ...

The positive CHMP opinion is based on a full multi-trial development program, culminating in the results from the pivotal phase-III trial ADVOCATE in 331 patients with ANCA-associated vasculitis in 20 ...

The reemergence of myeloperoxidase-antineutrophil cytoplasmic antibodies — or MPO-ANCA — can serve ... remission in MPO-ANCA–positive ANCA-associated vasculitis, according to findings ...

These clinical, microscopic, and laboratory findings are consistent with previously reported cases of PTU-induced ANCA-positive vasculitis, and thus the patient was given that diagnosis.

Unfortunately, in rare diseases like ANCA-associated vasculitis there is limited clinical trial data available to guide treatments. This meta-analysis is a good attempt to give clinicians guidance ...

Idiopathic ANCA-associated vasculitis (AAV) that is double-positive for MPO-ANCA and PR3-ANCA is associated with worse remission rates compared with MPO-AAV and PR3-AAV, according to investigators.

Cigarette smoking was associated with ANCA-associated vasculitis, particularly myeloperoxidase ANCA-positive vasculitis, according to data published in JAMA Internal Medicine. “We have an ...