AMPK会抑制mTOR，从而启动自噬。 此外，ATG家族基因（Autophagy-related genes）在自噬过程中也起到了关键的信号传导作用，许多自噬相关的遗传变异会 ...

Aging involves gradual functional decline across various biological systems, including impaired cellular mechanisms such as ...

Figure 2. Entosis is induced by long-term starvation. (A) Short-term starvation for glucose induces AMPK-dependent autophagy and nutrient recycling (left). Long-term glucose starvation induces ...

AMPK is associated with many anti-aging-related cellular processes, such as proteostasis, mitochondrial biogenesis, autophagy, mitohormesis, inflammation, and neurodegeneration. Therefore ...