会议以多个独立主题的报告形式开展，覆盖了从非临床到临床、从体外到体内、从定性到定量等多个ADME研究的维度，报告内容包括指导原则解读和 ...

为探究膀胱癌（BLCA）预后相关因素，研究人员构建 17 基因 ADME 风险预测模型，助力临床决策。 膀胱癌是全球常见癌症之一，每年约有 57.3 万新发病例，虽整体 5 年生存率接近 78%，但转移性膀胱癌患者的总生存率急剧下降至 6% 以下，且约一半的肌肉浸润性膀胱 ...

此外，S14也可能通过其他关键途径具有AKI治疗的潜力。随后，ADME研究表明，S14在体内的生物转化发生迅速，转化为S14-葡萄糖醛酸盐，然后从体内 ...

Promega公司与位于马里兰州巴尔的摩市的Celsis In Vitro Technologies (Celsis IVT) 将在原代肝细胞内进行ADME/Tox的试验和推测工作。Promega ...

智通财经APP获悉，东阳光药 (01558)AI研发团队推出了多个自研创新模型应用于药物分子ADME/T属性优化，已涵盖PK曲线预测和CYPs相互作用预测。近日，团队发布了基于多任务学习策略的药物透膜/转运预测模型，内部数据测试的受试者工作曲线下面积 ...

ADME is the abbreviation for Absorption, Distribution, Metabolism and Excretion. ADME studies are designed to investigate how a chemical (e.g., a drug compound) is processed by a living organism.

Detailed information on sample metadata is given in Supplementary Table S1. Table 1 summarizes 21 of the 95 ADME associations that represent replications, including 3 exactly replicated eQTLs and ...

DUBLIN--(BUSINESS WIRE)--The "ADME-Toxicology Testing: Global Strategic Business Report" report has been added to ResearchAndMarkets.com's offering. Global ADME-Toxicology Testing Market to Reach ...

These efficiencies facilitated the development of standard-tiered in vitro ADME/DDI study options. Design and deliverable options can be tailored to each stage of the preclinical drug development ...

Experts discuss factors that can affect the outcome of an ADME study, signs that a drug compound shows promise, red flags, and key parameters to determine safety and efficacy. Absorption, distribution ...