Figure 1: Antibodies from AChR-Ab–seronegative MG patients bind to MuSK. Figure 3: MuSK IgG antibodies induce AChR clusters but inhibit agrin-induced clustering. COS7 cells were plated onto ...

The new report suggests patients with acetylcholine receptor (AChR) antibody titers above 8.11 nmol/L were at higher risk of conversion. Antibody titers in patients with acetylcholine receptor ...

The anti–acetylcholine receptor antibody is found in 70% to 90% of patients with generalized acquired MG, according to Medscape. 2 Since 2017, the FDA has approved 3 complement inhibitors and 2 ...

Idiopathic autonomic neuropathy is a severe, subacute disorder with a presumed autoimmune basis. It is indistinguishable from the subacute autonomic neuropathy that may accompany lung cancer or ...

Most people with generalized myasthenia gravis (gMG) have antibodies in their body that attack acetylcholine receptors at the neuromuscular junction, the place where nerve cells and muscle cells ...

People who suffer from the autoimmune disease myasthenia gravis experience muscle weakness that can affect any of the muscles we use to blink, smile or even move our body around. Researchers have ...

in adult patients who are anti-acetylcholine receptor (AchR) or anti-muscle-specific tyrosine kinase (MuSK) antibody positive. The company says Rystiggo is the only FDA-approved treatment in ...

The FDA has approved Imaavy™ (nipocalimab-aahu) for the treatment of generalized myasthenia gravis in patients aged 12 years and older who are AChR or anti-muscle-specific tyrosine kinase antibody ...

In myasthenia gravis, abnormal antibodies reduce the number of receptors for acetylcholine on muscle cells. You need acetylcholine receptors for your muscles to function normally. The antibodies ...

The results demonstrated durable and sustained efficacy of UPLIZNA in patients with acetylcholine receptor autoantibody-positive (AChR+) gMG with two doses a year, following an initial loading dose.

In the Phase 3 MG study, batoclimab met its primary endpoint of mean change from baseline in Myasthenia Gravis Activities of Daily Living (MG-ADL) score in acetylcholine receptor antibody positive ...

You’ll receive it weekly for 4 weeks, followed by every 2 weeks, and is approved for people who have tested positive for anti-acetylcholine receptor antibodies. Taking eculizumab may increase ...