which is the naturally occurring AAV serotype that is currently understood to have the best penetration of the BBB in humans. “We believe Voyager’s TRACER capsids should allow significantly ...
When AAV serotype 9 (AAV9) was systemically administered to mice with AAV neutralizing antibodies, the gene transfer efficiency in the brain and liver decreased to 5–15%. However, by loading ...
Together with the existing Vericheck ddPCR Empty-Full Capsid Kits for serotypes AAV5 and AAV9, the addition of the new kits for serotypes AAV2 and AAV8 extends the range’s suitability to approximately ...
The therapy utilizes a recombinant adeno-associated virus serotype 9 (rAAV9) capsid to deliver the human TRIM72 gene via intrathecal administration. Preclinical studies demonstrate TRIM72's ...