资讯

10. Bish, L.T., et al., Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat. Human gene therapy, 2008. 19(12): p.
这项研究通过筛选细胞穿膜肽与不同AVV的组合,获得了一种具有高效跨血脑屏障递送能力的AVV变体——AAV.CPP.16。 相信大家对血脑屏障(BBB)这个 ...
Grimm D. et al., Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype. J. Virology. 2006:80:426-439.
This is a summary of abstract #1280, "Adeno-Associated Virus Serotype-5 Delivery to the Rat Trigeminal Ganglion," which will be presented on Friday, March 21, 2014, 3:30 p.m. – 4:45 p.m. at the ...
AAV serotype considerations. Multiple AAV serotypes have been isolated from tissue culture stocks from humans and nonhuman primates. 39 To date, 13 distinct AAV serotype vectors ...
Bio-Rad Laboratories, Inc. (NYSE: BIO and BIO.B), announced the launch of Vericheck ddPCR™ Empty-Full Capsid Kits for adenoassociated virus (AAV) serotypes 2 and 8, enabling determination of capsid ...
Nakai’s team made some of the first improvements to the technology by enabling AAV to be tracked at the RNA level. 2 To do this, his team designed an AAV library composed of 25 recombinant AAV ...
A new research study titled Adeno-Associated Virus Serotype-5 Delivery to the Rat Trigeminal Ganglion will be presented today The objective of this study was to evaluate transduction efficiency of ...
Gene therapy pioneer James M. Wilson, M.D., Ph.D., and colleagues have detailed in a new study, instances of severe, life-threatening toxicity in monkeys and piglets given high doses of gene ...
1. Boutin S, et al. Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using ...