Oral fingolimod (FTY720/Gilenya; Novartis) is a first-in-class sphingosine 1-phosphate (S1P) receptor modulator that, in relapsing–remitting MS, has demonstrated improved efficacy compared to ...

FTY720 (fingolimod) is a structural analogue of sphingosine, an endogenous lysophospholipid, which targets sphingosine-1-phosphate receptors after biotransformation to FTY720-phosphate.

Oral fingolimod (FTY720) is a sphingosine-1-phosphate–receptor modulator. After phosphorylation, fingolimod acts as a functional antagonist of the sphingosine-1-phosphate type 1 receptor ...

The abstract, "Harnessing Biomaterial-Based FTY720 Immunotherapy to Accelerate Oral Wound Healing," was presented during the "Improving Drug Delivery for Cancer Therapy and Tissue Healing" Oral ...

Philadelphia, PA, March 13, 2012 – A new study suggests that administering FTY720, an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor ...

FREEDOMS study shows FTY720 reduced relapse rates by 54-60% compared to placebo, and disability progression by 30-32%[1] Results build on Phase III TRANSFORMS one-year study showing FTY720 reduced ...

Published today in Autophagy, the researchers found the drug (FTY720) had a potent effect in human ovarian cancer cells, even in those resistant to cisplatin, the most commonly used ...

ZURICH, Sept 30 (Reuters) - Swiss drugmaker Novartis AG said on Wednesday its FTY720 oral drug to treat multiple sclerosis reduced both relapses and disability progression. Initial results from ...

Combined data from TRANSFORMS and FREEDOMS studies show significant efficacy in reducing relapses, disability progression and MRI lesions in MS - In FREEDOMS, FTY720 0.5 mg dose reduced the risk ...

Fingolimod (FTY720) è un nuovo agente immunomodulante orale attualmente in fase di valutazione per il trattamento della sclerosi multipla recidivante. In questo studio proof-of-concept ...

FTY720 is a structural analogue of sphingosine that, after conversion to the biologically active FTY720-phosphate molecule, binds with high affinity to sphingosine-1-phosphate receptors to act as ...